Role of Postradiation Genome Instability in Evaluating the Development of Radiation-Determined Pathology in Children after the Chernobyl Accidentand Investigation Perspectives

Alla E. Sipyagina; Larisa S. Baleva; Nataliya M. Karakhan; Vladimir S. Sukhorukov; Milyausha K. Tagirova

doi:10.4028/www.scientific.net/AMR.1051.322

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1051Role of Postradiation Genome Instability in...

Role of Postradiation Genome Instability in Evaluating the Development of Radiation-Determined Pathology in Children after the Chernobyl Accidentand Investigation Perspectives

Abstract:

The role of genetic instability (inferred from cytogenetic parameters of chromosome aberrations) and nuclear DNA repair activity play in radiation-determined diseases (neoplasms, including malignancies; congenital disorders and malformations; and chromosomal disorders) is considered in children from regions varying in extent of soil contamination with cesium-137 after the Chernobyl Accident.

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Periodical:

Advanced Materials Research (Volume 1051)

Pages:

322-325

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1051.322

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Online since:

October 2014

Authors:

Alla E. Sipyagina, Larisa S. Baleva*, Nataliya M. Karakhan, Vladimir S. Sukhorukov, Milyausha K. Tagirova

Keywords:

Children of Various Age Groups, Cytogenetic Alterations, DNA Repair Activity, Genome Instability, Radiation, Radiation-Determined Pathology

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