Anti-Diabetic Activity of Polysaccharides from Agaricus bisporus Mycelia

Tao Ying Zhou; Xing Yuan Li; Nian You Chen; Zi Lin Wang; Liang Bin Yu; Hui De Yang; Yu Bi

doi:10.4028/www.scientific.net/AMR.1073-1076.1808

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 1073-1076Anti-Diabetic Activity of Polysaccharides from...

Anti-Diabetic Activity of Polysaccharides from Agaricus bisporus Mycelia

Abstract:

The present study was carried out to evaluate the anti-diabetic activity of polysaccharides from Agaricus bisporus mycelia (PABM) in alloxan-induced diabetes mellitus (DM) mice. After administration with 100, 200 and 400 mg/kg body weight of PABM to DM mice for 28 days, the effects of PABM on the body weight, blood glucose, serum insulin, total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels were monitored. The results showed that the PABM could increase body weight, serum insulin and HDL-C levels, as well as decrease TC, TG and LDL-C levels in DM mice. PABM possess anti-diabetic activity.

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Periodical:

Advanced Materials Research (Volumes 1073-1076)

Pages:

1808-1811

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1073-1076.1808

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Online since:

December 2014

Authors:

Tao Ying Zhou*, Xing Yuan Li, Nian You Chen, Zi Lin Wang, Liang Bin Yu, Hui De Yang, Yu Bi

Keywords:

Agaricus bisporus Mycelia, Anti-Diabetic, Blood Glucose, Cholesterol, High-Density Lipoprotein Cholesterol, Insulin, Low-Density Lipoprotein Cholesterol, Polysaccharides, Triglyceride

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* - Corresponding Author

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