Biological Dosimetry of the Irradiation Emitted by NG-12I Neutron Generator

Elena Kandakova; Andrey Vazhenin; Sergey Kiryushkin; Evgeniy Pryakhin; Aleksandr Akleev

doi:10.4028/www.scientific.net/AMR.1084.357

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1084Biological Dosimetry of the Irradiation Emitted by...

Biological Dosimetry of the Irradiation Emitted by NG-12I Neutron Generator

Abstract:

The aim of the present work was to carry out biological dosimetry of the irradiation generated by NG-12I system implementing the stem hemopoietic cells survival in CBA mice with the use of the test of exogenous colony formation. The rate of relative biological effectiveness (RBE) for radiation of NG-12I system, defined as a ratio of equal effective doses (in our research we used D0), amounted to 1.53 for an acute neutron irradiation and 3.05 for a fractionated neutron irradiation. Obtained data allows defining a total dose and one fraction dose of a neutron irradiation of NG-12I system for the complex photon-neutron therapy of oncological patients.

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Periodical:

Advanced Materials Research (Volume 1084)

Pages:

357-360

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1084.357

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Online since:

January 2015

Authors:

Elena Kandakova*, Andrey Vazhenin, Sergey Kiryushkin, Evgeniy Pryakhin, Aleksandr Akleev

Keywords:

Biological Dosimetry, Exotest Method, Marrow, Neutron Generator NG-12I, Neutron Radiation Fractionation, Photon-Neutron Therapy, Relative Biological Effectiveness (RBE), Stem Cells

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