Breast Scintigraphy with 199Tl in Diagnosis of Breast Cancer

Anna Titskaya; Vladimir Chernov; Elena Slonimskaya; Ivan Sinilkin; Roman Zelchan

doi:10.4028/www.scientific.net/AMR.1084.361

Paper Titles

X-Ray Absorption Coefficient Behavior Depending on Disposition of Diffraction Vector and Temperature Gradient Vector
p.342

Application of Digital Auskultometer in Radiotherapy
p.349

Application of NANOcolloid Materials Labeled by Radionuclides in Medicine
p.352

Biological Dosimetry of the Irradiation Emitted by NG-12I Neutron Generator
p.357

Breast Scintigraphy with ¹⁹⁹Tl in Diagnosis of Breast Cancer
p.361

Combined Modality Treatment Including Neutron Therapy for Tumors of the Nasal Cavity and Paranasal Sinuses
p.365

Development of the Binary Technologies for Radiation Therapy of Malignant Tumors – Current State and Problems
p.369

Diagnostic Efficiency of Single-Photon Emission Computed Tomography with ^99MTc-MIBI in Visualization of Malignant Tumors of the Larynx and Laryngopharynx
p.373

Dynamic Renoscintigraphy with 99mTc-DTPA in the Evaluation of Renal Function in Patients with Chronic Heart Failure
p.377

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1084Breast Scintigraphy with 199Tl in Diagnosis of...

Breast Scintigraphy with ¹⁹⁹Tl in Diagnosis of Breast Cancer

Abstract:

To study the diagnostic capabilities of emission single photon computed tomography with ¹⁹⁹Tl in imaging of breast cancer 90 women with breast diseases were included in the study. During the research high indications of specificity 96.7% were obtained in the detection of breast cancer. The sensitivity of breast cancer visualization was 95%, while in the detection of tumors smaller than 10mm, the sensitivity was 75%, in detecting tumors more than 10mm - 98%. Considering the high sensitivity and specificity of SPECT with ¹⁹⁹Tl, we can recommend the use of this method as an additional diagnostic criterion in cases where other methods of radiation diagnosis and the results of morphological studies do not provide a clear answer.

You might also be interested in these eBooks

Radiation and Nuclear Techniques in Material Science

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 1084)

Pages:

361-364

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1084.361

Citation:

Cite this paper

Online since:

January 2015

Authors:

Anna Titskaya, Vladimir Chernov, Elena Slonimskaya, Ivan Sinilkin, Roman Zelchan*

Keywords:

¹⁹⁹T, Breast Cancer, Breast Scintigraphy, Sensitivity, Specificity

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] A.M. Granov, L.A. Tyutin, M.S. Tolstanova, The application of positron emission tomography with 18- fluorodeoxyglucose in clinical oncology, Problems in Oncology (Voprosy onkologii, in Russian) 49 (5) (2003) 563-573.

Google Scholar

[2] A. Aziz, R. Hashmi, Y. Ogawa, Tc-99m – MIBI scintimammography; SPECT versus planar imaging. J. Cancer Bioter. Radiopharm. 14 (6) (1999) 495-500.

DOI: 10.1089/cbr.1999.14.495

Google Scholar

[3] C.K. Kuhl, MRI of the breast cancer. J. Eur. Radiol. 10 (2000) 46-58.

Google Scholar

[4] S.J. Kim, Y.T. Bae, J.S. Lee , I.J. Kim, Y.K. Kim, Diagnostic performances of double-phase tc-99m MIBI scintimammography in patients with indeterminate ultrasound findings: visual and quantitative analyses. J. Ann. Nucl. Med. 21 (3) (2007).

DOI: 10.1007/s12149-006-0002-y

Google Scholar

[5] W. Yu. Ussov, J.E. Riannel, J.M. Michailovic, Quantification of breast cancer blood flow in absolute units using Rutland-Patlak analysis of 99mTc MIBI uptake. Reviews in Nucl. Med. - Countries of Central and east Europe 2(2) (1999) 36-44.

Google Scholar

[6] S.V. Kanaev, S.N. Novikov, P.V. Krivorot'ko, V.F. Semiglazov, P.I. Kryzhevitskii, Interpretation of breast imaging with 99mTc-MIBI by semiquantitative lesion characterization, Problems in Oncology (Voprosy onkologii – in Russian) 58 (6) (2012).

Google Scholar

[7] K. Koizumi, K. Toyama, T Araki, Uptake of Tc-99m tetrafosmin, Tc-99m MIBI and 201Tl in tumour cell line, J. Nucl. Med. 37 (1996) 1551-1556.

Google Scholar

[8] A. Sehweil, J.H. McKillop, R. Milroy, 201Tl scintigraphy in the staging of lung cancer, breast cancer and lymphoma, Nucl. Med. Commun. 1(4) (1990) 263-269.

DOI: 10.1097/00006231-199004000-00002

Google Scholar

[9] Yu.B. Lishmanov, V.I. Chernov, N.G. Krivonogov, Experimental perfusion scintigraphy using 199Tl chloride, Medical Radiology and Radiation Safety (Meditsinskaya radiologiya i radiatsionnaya bezopasnost', in Russian) 3 (1988) 13-16.

Google Scholar

[10] Yu.B. Lishmanov, V.I. Chernov, Myocardial scintigraphy in nuclear cardiology, TSU Publishing House, Tomsk, (1997).

Google Scholar

[11] R.P. Spencer, Tumour-seeking radiopharmaceuticals: nature and mechanisms, J. Nucl. Med. 2 (1994) 649-662.

Google Scholar