Bioactivity and Physico-Chemical Properties of Composites on Basis of Hydroxyapatite with Lactic and Glycolic Acids Oligomers

Lyudmila A. Rasskazova; Darya Lytkina; Elena Shapovalova; Vladimir V. Botvin; Maksim A. Pozdnyakov; Ilya Zhuk; Anatoliy G. Filimoshkin; Natalya Korotchenko; Vladimir Kozik

doi:10.4028/www.scientific.net/AMR.1085.394

Paper Titles

Opisthorchis felineus Infection and Harmful Metals Bio-Concentration: A Pilot Study in Hamster Model
p.370

Study of MWNTS Influence upon Liver Histological and Histochemical Parameters in Laboratory Mice: Preliminary Results
p.376

Effect of Platinum Nanoparticles on Biological Activity of Humus-Accumulated Horizons
p.384

Influence of Slaked Lime Addition on Biotechnological Specification of Vermicultivation
p.390

Bioactivity and Physico-Chemical Properties of Composites on Basis of Hydroxyapatite with Lactic and Glycolic Acids Oligomers
p.394

Reduction of Locomotor and Brain Activity of Wistar Rats after Serial Administration of Titanium Dioxide
p.400

Circulating Matrix Metalloproteinases, Tissue Inhibitors, Natriuretic Peptides, and Rigidity of the Great Arteries in Patients with HFpEF in 12 Month after Myocardial Infarction
p.406

Organ-Preserving Surgery Using Endografts from Superelastic Titanium-Nickelid-Based Alloy for Patients with Laryngeal Cancer
p.414

Effect of Plasma-Based Chemical Modification on Wettability of Polymer Materials for Cardiovascular Surgery
p.419

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1085Bioactivity and Physico-Chemical Properties of...

Bioactivity and Physico-Chemical Properties of Composites on Basis of Hydroxyapatite with Lactic and Glycolic Acids Oligomers

Abstract:

A new method in situ for producing of biocompatible composites based on hydroxyapatite and oligomers of lactic and glycolic acid is described. Their thermo-mechanical, physical-chemical and biological properties are studied as well. The formation of bonds between hydroxyapatite with lactic and glycolic oligomers in composites are confirmed by IR spectroscopy of the samples, including those obtained in the Soxhlet apparatus. The formation of calcium-phosphate layer on the composite's surface containing hydroxyapatite was shown by SBF-investigation. The scaffolds based on lactic acid oligomer do not stimulate formation of a calcium-phosphate layer and they are subjected to destruction by the way of hydrolysis.

You might also be interested in these eBooks

Prospects of Fundamental Sciences Development

View Preview

Info:

Periodical:

Advanced Materials Research (Volume 1085)

Pages:

394-399

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1085.394

Citation:

Cite this paper

Online since:

February 2015

Authors:

Lyudmila A. Rasskazova, Darya Lytkina, Elena Shapovalova, Vladimir V. Botvin, Maksim A. Pozdnyakov, Ilya Zhuk, Anatoliy G. Filimoshkin, Natalya Korotchenko, Vladimir Kozik

Keywords:

Bioactive Composites, Glycolic Acids Oligomers, Hydroxyapatite (HA), Lactic, Microwave Synthesis, SBF Investigation, Synthesis In Situ

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] M. Sadat-Shojai, M. Khorasani, E. Dinpanah-Khoshdargi, A. Jamshidi, Synthesis methods for nanosized hydroxyapatite with diverse structures, Acta Biomaterialia. 9 (2013) 7591-7621.

DOI: 10.1016/j.actbio.2013.04.012

Google Scholar

[2] S.V. Barinov, V.S. Komlev, Bioceramics based on calcium phosphates, Science, Moscow, (2005).

Google Scholar

[3] Ben-Nissan B. Advances in Calcium Phosphate Biomaterials, Spinger, (2014).

Google Scholar

[4] M. Shtilman, The polymers of medical and biological applications, Akademkniga, Moscow, (2006).

Google Scholar

[5] B.I. Sevastyanov, M.P. Kirpichnikov, Biocompatible materials, Medical informational agency, Moscow, (2011).

Google Scholar

[6] L. Hench, J. Jones, Biomaterials, artificial organs and tissue engineering, Woodhead Publishing, Cambrige, (2005).

Google Scholar

[7] N.M. Korotchenko, L. A Rasskazova, Rus. Fed. Patent 2, 507, 151. (2014).

Google Scholar

[8] T. Kokubo, H. Takadama, How useful is SBF in predicting in vivo bone bioactivity? Biomater. 27 (2006) 2097-2915.

DOI: 10.1016/j.biomaterials.2006.01.017

Google Scholar