Preparation of HA Hydrogel by Click Chemistry

Yuan Cui; Jing Peng Zhang; Wei Zhang; Qian Duan

doi:10.4028/www.scientific.net/AMR.1088.286

Paper Titles

Influence of Solid-Liquid Composite Casting on Interface and Microstructure of High Chromium Cast Iron
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The Effect of Forming Speed on the Formability of a Zr-Based Bulk Metallic Glass
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Development and Application of Manganese Cobalt Lithium Compounds in the Field of Lithium Batteries
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Bi-(2, 4-dihydro-2H-3-(4-N-maleimido) phenyl-1,3-benzoxazine) Isopropane: Molecular Structure, Optical Spectrum and Thermodynamic Properties
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Preparation of HA Hydrogel by Click Chemistry
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Synthesis and Properties of Functionalized Sulfur-Containing Hexa-Peri-Hexabenzocoronene
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Morphology of Cobalt Oxalate Powders Prepared with Pulsed Electromagnetic Field
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Synthesis, Crystal Structure and Characterizations of a Novel Open-Framework Lanthanide Imidazoledicarboxylate
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1088Preparation of HA Hydrogel by Click Chemistry

Preparation of HA Hydrogel by Click Chemistry

Abstract:

"Click chemistry" was used in this paper to get a novel hyaluronic acid (HA) hydrogel by modified HA molecules' side chains with azide and alkynyl groups to perform "Click" reaction. The HA hydrogel can be achieved "in situ" injection gel. The properties of the HA hydrogel can be controlled by controlling the amount of alkynyl and azide groups on side chains to achieve controllable HA hydrogel by HA molecular design. The reactant, product and hydrogel were characterized by ¹H NMR, FTIR and morphology observation to determine the processes of reaction and can hydrogel formation.

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Periodical:

Advanced Materials Research (Volume 1088)

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286-289

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https://doi.org/10.4028/www.scientific.net/AMR.1088.286

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Online since:

February 2015

Authors:

Yuan Cui*, Jing Peng Zhang, Wei Zhang, Qian Duan

Keywords:

Alkynyl Group, Azide, Click Chemistry, Hyaluronic Acid

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