Surface Morphology of Herbal Prepared Using Nanotechnology

Abstract:

Herb have been the basis of traditional medicines throughout the world for thousands of years and continue to provide new remedies to humankind In this study, Polygonum minus (kesum) nanoparticles were prepared by using planetary ball mill and analysis for their physical and morphology properties. The size reduction method had a distinct effect on physical and morphology properties of Polygonum minus analyzed. The surface morphology and roughness of nanoherb was analyzed by using Field Emission Scanning Electron Microscope (FSEM) and Atomic Force Microscope (AFM). The result showed that after ball milling, the average size of particles was produced in range 227-241nm which was significantly smaller than the 100 μm prepared by conventional rotor mixer. Higher degree of granule surface fractured was observed as a result of a planetary ball milling process based on FESEM images.

• Periodical: Advanced Materials Research (Volume 1109)
• Pages: 328-332
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.1109.328
• Online since: June 2015
• Authors: A.S. Nadzirah*, Mohammad Rusop, I. Abdul Latif
• Keywords: AFM, FESEM, Nanoherb, Planetary Ball Mill, Polygonum minus

References

[1] M. Quintanilla-Carvajal, B. Camacho-Díaz, L. Meraz-Torres, J. Chanona-Pérez, L. Alamilla-Beltrán, A. Jimenéz-Aparicio, Nanoencapsulation: A new trend in food engineering processing, Food Engineering Reviews. 2(2010) 39–50.

DOI: 10.1007/s12393-009-9012-6

[2] H. Bouwmeester, S. Dekkers, M. Y. Noordam, W. I. Hagens, A. S. Bulder, C. D. Heer, S. E. C. G. Ten Voorde, S. W. P. Wijnhoven, H. J. P. Marvin, Review of health safety aspects of nanotechnologies in food production. Regulatory Toxicology and Pharmacology. 53 (2009) 52-62.

DOI: 10.1016/j.yrtph.2008.10.008

[3] V. J. Mohanraj, Y. Chen, Nanoparticles – A Review. Tropical Journal of Pharmaceutical Research. 5 (2006) 561-573.

[4] C. Monica, R. Cremonini, Nanoparticles and higher plants. Caryologia. 62(2009) 161-165.

DOI: 10.1080/00087114.2004.10589681

[5] M. Cushen, J. Kerryb, M. Morrisc, M. Cruz-Romerob, E. Cummins , Nanotechnologies in the food industry – Recent developments, risks and regulation, Trends in Food Science & Technology. 24 (2012) 30-46.

DOI: 10.1016/j.tifs.2011.10.006

[6] Q. Chaudhry, M. Scotter, J. Blackburn, B. Ross, A. Boxall, L. Castle, R. Aitken, R. Watkins, Review: Applications and implications of nanotechnologies for the food sector, Food Additives and Contaminants. 25 (2008) 241–258

DOI: 10.1080/02652030701744538

[7] S. S. Bhadoriya, A. Mangal, N. Madoriya, P. Dixit, Bioavailability and Bioactivity Enhancement of Heral Drugs by "Nanotechnology" : A Review, Journal of Current Pharmaceutical Research. 8 (2011) 1-7.

[8] H. D. Chen, J. C. Weiss, F. Shahidi, Nanotechnology in nutraceuticals and functional foods, Food Technology. 25 (2006) 30-36.

[9] T. Takatsuka, T. Endo, Y. Jianguo, K. Yuminoki, N. Hashimoto, Nanosizing of Poorly Water Soluble Compounds Using Rotation/Revolution Mixer, Chem. Pharm. Bull. 57 (2009)1061-1067.

DOI: 10.1248/cpb.57.1061

[10] X. Zhao, Z. Yang, G. Gai, Y. Yang, Effect of superfine grinding on properties of ginger powder, Journal of Food Engineering. 91 (2009) 217–222

DOI: 10.1016/j.jfoodeng.2008.08.024

[11] M. Z. Borhan, R. Ahmad, M. Rusop, S. Abdullah, Optimization of ball milling parameters to produce Centella asiatica herbal nanopowder, Journal of Nanostructure in Chemistry. 3 (2013) 79.

DOI: 10.1186/2193-8865-3-79

[12] J. C. Liu, Z. G. Jiao, X. H. Liang, L. Han, H. Liu, Effect of Ultrafine Pulverization on Properties of Apple Pomace Powder, Advanced Materials Research. Volx 236 – 238 (2011) 2560-2563.

DOI: 10.4028/www.scientific.net/amr.236-238.2560

[13] J. R. Liu, G. F. Chen, H. N. Shih, P. C. Kuo, Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology, Phytomedicine. 15 (2008) 23-30.

DOI: 10.1016/j.phymed.2007.11.012

[14] Y. I. Su, Z. Y. Fu, C. J. Quan, W. M. Wang, Fabrication of nano Rhizama Chuanxiong particles and determination of tetramethylpyrazine, Transactions of Nonferrous Metals Society of China. 16 (2006) s393-s397.

DOI: 10.1016/s1003-6326(06)60218-5

[15] J. Lee, Drug nano- and microparticles processed into solid dosage forms: physical properties, J. Pharm. Sci. 92 (2003) 2057–2068.

DOI: 10.1002/jps.10471

[16] A. Charkhi, H. Kazemian, M. Kazemeini, Optimized experimental design for natural clinoptilolite zeolite ball milling to produce nano powders, Powder Technology. 203 (2010) 389–396.

DOI: 10.1016/j.powtec.2010.05.034

[17] S. Yashvanth, S. S. Rani, A. S. Rao, S. S. Madhavendra, Microscopic and micro chemical evaluation (elemental Analysis) of the medicinal herb, Lippia nodiflora (Linn.) Rich (Phyla nodiflora Linn. Green), Asian Pacific Journal of Tropical Disease. (2012) S124-S129 .

DOI: 10.1016/s2222-1808(12)60137-6