Nanoceramics Composite Biomaterials in the Calcium Carbonate-Hydroxyapatite System
Composite powders in the calcium carbonate (CC) – hydroxyapatite (HA) system with carbonate content up to 50 wt. % were synthesized by the precipitation from aqueous solution and characterized in detail. Specific area of the powders decreases with an increase in carbonate content due to appearance of large elongated CC crystals of about 0,5 micrometer size. The use of highly active to sintering nanodisperse powders resulted in lowering of sintering temperature below 7200C, preventing thermal decomposition. Ceramics of about 20 wt.% carbonate content revealed the highest strength of about 77 MPa, having the grain size of about 100 nm. According to in vitro testing, the materials are non toxic for human fibroblast cells.
Joong Hee Lee
M. Goldberg et al., "Nanoceramics Composite Biomaterials in the Calcium Carbonate-Hydroxyapatite System", Advanced Materials Research, Vols. 123-125, pp. 339-342, 2010