The nonferrous alloy castings will be much demanded with the development of aerospace, light-weight weapons and automotive industry. Casting CAD/CAE technology has played an increasingly important role in foundry. It can help technician to design casting process and simulate heat transferring and molten metal flowing before actual production. Firstly, the main contents and basic principles, mathematical models of casting CAD and CAE were introduced. Secondly, the casting CAD/CAE technology route was interpreted, and then several CAD/CAE applications of casting process design and simulating were carried out on nonferrous alloys, such as aluminum, magnesium and copper. The results indicate that CAD/CAE technology can be applied to casting process design and predict casting defects which usually occur during the casting mold filling and solidification process, it can provide references to optimize casting process, so as to improve casting quality, reduce the rejection rate and shorten the development cycle of new products.