Variation of Absorption Coefficient of Glucose Water in Consideration of Water Displacement

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Adding glucose in water will cause two influences on the aqueous solution: one is absorption coefficient addition of glucose; the other is absorption coefficient decrease of water because of water displacement. So the total absorption effect is the result of the absorption coefficient increase of glucose and absorption coefficient decrease of water. In this paper the absorption coefficient of glucose water is analyzed in consideration of water displacement. By data of handbook, we deduce a relationship between the glucose absorption coefficient addition and water absorption coefficient decrease. When one molar glucose is added into water, 6.15 molars water molecular is displaced. The wavelength selection in glucose detection should be at the place where the combined absorption is maximum. The wavelength of widely used in blood glucose concentration detection, e.g. 1.6μm, is selected as an example for analysis. When glucose is added into water, the linear relationship between glucose concentration and absorption coefficient is hold on. On the other hand, when the water molecular is decreased, the water absorption coefficient will decreased, too, which will decrease the total absorption coefficient compared to the situation without water displacement. In general, water displacement will decrease the sensitivity of absorption coefficient to glucose concentration.

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358-362

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December 2010

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© 2011 Trans Tech Publications Ltd. All Rights Reserved

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[1] Xu Kexin, Gao Feng and Zhao Huijuan:Biomedical photonics (Science press, Beijing 2007).

Google Scholar

[2] Matthias Kohl, Matthias Essenpreis and Mark Cope: The influence of glucose concentration upon the transport of light in tissue-simulating phantoms. Physics in medicine and biology, Vol. 40 (1995), pp.1267-1287.

DOI: 10.1088/0031-9155/40/7/009

Google Scholar

[3] Robert C. Weast and Melvin J. Astle: CRC handbook of chemistry and physics, 63th ( CRC press, Boca Raton, D-239 1982).

Google Scholar

[4] R. D. Rosenthal, L. N. Paynter, and L. H. Mackie: Noninvasive measurement of blood glucose. U.S. Patent 5028787. (1991).

Google Scholar

[5] Hoeil Chung, Mark A. Arnold, Martin Rhiel and David W. Murhammer: Simultaneous measurements of glucose, glutamine, ammonia, lactate, and glutamate in aqueous solution by near infrared spectroscopy. Applied spectroscopy, Vol. 50(2), (1996).

DOI: 10.1366/0003702963906447

Google Scholar

[6] Stephen F. Malin, Timothy L. Ruchti, Thomas B Blank, et al: Noninvasive prediction of glucose by near infrared diffuse reflectance spectroscopy. Clinical chemistry, Vol. 45(5), (1999), pp.1651-1658.

DOI: 10.1093/clinchem/45.9.1651

Google Scholar

[7] Stanley M. Dunn, Alkis Constantinides, Prabhas V. Moghe: Numerical methods in biomedical engineering (China machine press, Beijing 2009).

Google Scholar