Preparation and Characterization of Electrospun Silk Fibroin-Based Tubular Scaffolds

Ji Wei Huang; Feng Zhang; Bao Qi Zuo; Zhi Hai Fan; Huan Xiang Zhang

doi:10.4028/www.scientific.net/AMR.175-176.197

Paper Titles

Research on Structure and Property of Silk Fibroin Modified Viscose Fiber
p.176

Characterization of Angiogenesis during Skin Wound Repair by Porous Silk Fibroin Film
p.181

Biosynthesis of β-Glucosidase-Silk Fibroin Nanoparticles Conjugates and Enzymatic Characteristics
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Study on Optimization of Fermentation Condition for Nitrilase-Producer Escherichia Coli BL21 (DE3)/pET-Nit
p.192

Preparation and Characterization of Electrospun Silk Fibroin-Based Tubular Scaffolds
p.197

Structure and Properties of Bombyx Mori Silk Fiber Modified by Extract of Cactus
p.202

Effect of Metal Ions (Trivalent Chromium Ion and Copper Ion) on Light-Degradation of Silk Fabric
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Imine Bond Characterization and Properties for Controlled Release Drugs of Collagen Protein Cross-Linked Cotton Fiber
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In Vitro Evaluation of the Growth and Migration of Schwann Cells on Electrospun Silk Fibroin Nanofibers
p.220

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 175-176Preparation and Characterization of Electrospun...

Preparation and Characterization of Electrospun Silk Fibroin-Based Tubular Scaffolds

Abstract:

Artificial nerve conduits (NC) can be used as an alternative to autologous nerve grafts to enhance the repair of small nerve gaps. Many natural and synthetic biomaterials have been processed to be tubular scaffolds. However, current NC lack adequate molecular and structural functionalities. Thus, we prepared silk fibroin (SF)-based nanofibrous tubular scaffolds (inner diameter=1.5 mm) for nerve repair. The Bombyx mori silk fibroin was firstly dissolved in hexafluoroisopropanol (HFIP), and then was electrospun to be nanofibrous silk fibroin tube which topographically functionalized with aligned and non-aligned SF nanofibers. Effects of electrospinning parameters (including collection distance, rotational speed and translational speed) on the micro-morphology of SF tube were investigated. The nanofibers orientation in SF tube affects the mechanical property of SF tube. The results suggest that this tubular scaffold shows promising application in nerve tissue engineering.

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Advanced Materials Research (Volumes 175-176)

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197-201

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https://doi.org/10.4028/www.scientific.net/AMR.175-176.197

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Online since:

January 2011

Authors:

Ji Wei Huang, Feng Zhang, Bao Qi Zuo, Zhi Hai Fan, Huan Xiang Zhang

Keywords:

Electro-Spinning, Silk Fibroin, Tubular Scaffold

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