In this study, a temporarily solubilised disperse dye was prepared and applied to polyurethane/silk blend to probe a new dyeing technology. The effect of pH on the dyeing of this blend at different dyeing temperatures was investigated. The optimum dyeing condition was found to be 75 °C and pH 8 at which the dyeing rate curves for two components in blend was measured respectively. Because of difference in substantivity, the transfer of dye from polyurethane fiber to silk occurred during dyeing of the blend. the dyeing equilibrium was nearly achieved by increasing the dyeing time to 80 min. Even distribution of dye between polyurethane and silk, higher exhaustion on polyurethane fiber or fixation on silk as well as desirable fastness properties were obtained with this dye.