Many nanotech-based fabrics products and applications are already in use for textile finishing process in many countries. The industry aims at taking advantage of the opportunities of new nanomaterials while producing safe and ecological textiles. However, some concerns have been raised regarding the potential of engineering nanoparticles to have a negative impact of the human health and the environment. Up to now there are only few toxicological research and safe assessment done on the release of engineered nanoparticles from such products. This article summarizes the coping strategies and risk management of some developed countries and outlines the necessity of prospect research and risk assessment for nanotechnology potential hazards and technical uncertainty of nano-coated textiles to the environment and public health. The author believed the responsive regulations will allow for prevention and treatment of a nano-textiles’ life-cycle risks and support the safe, responsible development of nanotechnology while providing favorable conditions for textile industrial innovation to ensure that research and technological development is translated into affordable and safe wealth-generating products and processes.