Inducible Nitric Oxide Synthase (iNOS) Expression in Cirrhotic Patients with Hepatopulmonary Syndrome

Abstract:

The aim of this study was to define that the expression of inducible nitric oxide synthase (iNOS)in cell blocks from ascites was a certain value to evaluate hepatopulmonary syndrome(HPS). iNOS can stimulate the liver and lung to produce excess NO. Excessive production of NO can cause pulmonary vasodilatation and impaire arterial oxygenation. HPS is characterized by shortness of breath and hypoxemia caused by impaired arterial oxygenation due to pulmonary microvascular dilatation in patients with liver disease or PTH. Therefore.the positive rates of iNOS was a certain value to evaluate the conditions of HPS.

• Periodical: Advanced Materials Research (Volumes 183-185)
• Pages: 2207-2210
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.183-185.2207
• Online since: January 2011
• Authors: Li Fang Sun, Bing Quan Zhang, Na Zhang, Yan Ying Wang, Jing Yu
• Keywords: Hepatopulmonary Syndrome, Inducible Nitric Oxide Synthase

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