Effects of pH and Aeration on the Production of Docosahexaenoic Acid by Thraustochytrium aureum in Controlled Batch Fermentor Cultures
Docosahexaenoic acid (DHA. C22:6 ω-3) is an important structural component of neural and retinal tissues .The DHA yield was highest at pH5.5. Glucose and maltose utilization were similar as a function of pH, linseed oil consumption increased at pH 5.5, indicating that the formation of DHA from linseed oil at pH5.5 was of increased importance. Increased aeration resulted in doubling of T. aureum cell dry weights, increasing DHA yields and increasing in the maximum DHA -specific production rate .
Yanguo Shi and Jinlong Zuo
G. Yang et al., "Effects of pH and Aeration on the Production of Docosahexaenoic Acid by Thraustochytrium aureum in Controlled Batch Fermentor Cultures", Advanced Materials Research, Vols. 183-185, pp. 50-54, 2011