Multi-type vehicle open vehicle routing problem is logistics optimization indispensable part. Hybrid genetic algorithm is used to optimize the solution. Firstly, use sequence of real numbers coding so as to simplify the problem; Construct the targeted initial solution to improve the feasibility; adopt some arithmetic crossover operator to enhance whole search ability of the chromosome. Secondly, Boltzmann simulated annealing mechanism for control genetic algorithm crossover and mutation operations improve the convergence speed and search efficiency. Finally, comparing to standard genetic algorithm, simulation results demonstrate the effectiveness and good quality.