Microwave heating was efficient and the regeneration time was shortened compared to conventional thermal heating. Experiments were conducted to demonstrate that spent zeolite can be regenerated for reuse by microwave irradiation. The spent zeolite tested was prepared from the aqueous solutions of methylene blue. The effects of microwave irradiation time, microwave power on the regeneration efficiency were presented. The results show that microwave irradiation time and microwave power played significant role on the regeneration efficiency. It was concluded that microwave irradiation may be effective method for dye-loaded zeolite reuse.