A finite element analysis (FEA) model was proposed to predict the behavior of concrete-filled steel tubular (CFST) columns at overall stage of fire combined load based on ABAQUS. The whole stage includes initial loading, heating, cooling and post-fire phases. Accurate thermal and material model, element type, and solution method were chosen reasonably in the model considering the temperature and combined load. Due to lacking of test data about multi-phase of fires, the FEA model was verified with tests at different stages respectively. Some experimental specimens under different thermal and mechanical conditions were modeled using the FEA model, and the results obtained have good agreement with the experimental results. The mechanism of the CFST columns after exposure to overall stage of fire was also investigated based on the model.