Study on the Preparation, Property and Drug Release Carrier of Chitosan-Based Nanoparticles for Cancer Treatment
In this paper, the effective nanocompoties (EFNCs) as drug carriers are prepared by grafting reaction of cationic chitosan (CS) and anionic tripolyphosphate (TPP) to encapsulate cancer therapeutic agents such as berberine (BB), KCY-24B…etc. These EFNCs were featured by ultra violet–visible-near infrared spectrophotometer (UV-VIS-NIR spectrophotometer), fourier transform infrared spectrophotometer (FT-IR), zetasizer, transmission electron microscope (TEM) and field-emission scanning electron microscope (FESEM). So we can obtain here the synthetic method, characterization, and functionality of these effective nanoparticles.
Xiaoming Sang, Pengcheng Wang, Liqun Ai, Yungang Li and Jinglong Bu
C. W. Chou et al., "Study on the Preparation, Property and Drug Release Carrier of Chitosan-Based Nanoparticles for Cancer Treatment", Advanced Materials Research, Vols. 284-286, pp. 1800-1803, 2011