The Study on the Apoptosis of Rat’s Granule Cells Induced by Ethanol
To drink excessively for long time would damage human genital system seriously, nevertheless there is still less researches on the effect of ethanol to granule cells. Here we adhibit means of TUNEL coloration and flowcytometry examination and treat ex vivo granule cells with ethanol at different chroma and time. The result shows that ex vivo granule cells treated with ethanol at different chroma and time can be observed distinctly the morphologic character of cell apoptosis, and the percentage of apoptosis of ex vivo granule cells induced by ethanol would increase in a certain bound of chroma and time as the increasing of the chroma and time, indicating that ethanol can produce dysgenesia by inducing the apoptosis of granule cells of ovaries. The damage of ethanol for granule cells arouses people to control drinking and nip drinking evil in the bud, which is a world of practical importances for human’s procreate and health.
Jinglong Bu, Pengcheng Wang, Liqun Ai, Xiaoming Sang, Yungang Li
S. F. Li et al., "The Study on the Apoptosis of Rat’s Granule Cells Induced by Ethanol", Advanced Materials Research, Vols. 287-290, pp. 116-119, 2011