Recently revival made denim a prompting material in fashion throughout the world. For footwear design, denim as textile is the hot spot instead of animal leather in 2011. In this report the application of denim in footwear design is discussed. Denim has its specificity in aesthetic aspect. Also compared with leather, denim is more comfortable and healthy to wear. Designers have more freedom in decoration, painting, and composite material selections with denims in shoe design. The issues in manufacture of denim shoes are also mentioned in this work.