In this paper, with the ANSYS, stress distribution and safety factor of stationary power generation diesel engine connecting rod were analyzed by using 3D finite element method. The results show that the position of maximum principal stress is transition location of small end and connecting rod shank at maximum compression condition. The value of stress is 176 MPa in dangerous position. Maximum deformation is 0.0713mm. Safety factor is 1.86. The oil-hole of small end is the exposed destructive positions at maximum stretch condition. Maximum stress value is 67.7 MPa in dangerous position. Maximum deformation is 0.0145mm.