Constructing a Syntheses Table of the Standard Amino Acid Based on the PAM250 Matrix

Abstract:

It is well known that there are some similarities among various naturally occurring amino acids. The standard amino acids have been grouped by their general properties and the chemical structures of their side chains. In this paper we divided the molecular weight of amino acid into two parts: backbone molecular weight M_b and side chain molecular weight M_s. We naturally grouped the amino acids into two sets according to the rate of M_s / M_b. We developed a method to construct a syntheses table to reflect the relevant physicochemical properties based on the PAM250 matrix and successfully established an elegant table of the twenty amino acids. Our work proved that PAM250 matrix could be used not only in finding reasonable alignments but also in grouping similar amino acid.

• Periodical: Advanced Materials Research (Volumes 335-336)
• Pages: 1279-1284
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.335-336.1279
• Online since: September 2011
• Authors: Xiao Hong Shi, Xiang Hong Wang
• Keywords: Classification, Graphical Theory, Pam250 Matrix, Similar Property, Standard Amino Acid, Syntheses Table

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