Medium Optimization for the Antibacterial Substances Production from Brevibacillus brevis XDH Using Response Surface Methodology

Abstract:

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Brevibacillus Brevis XDH is an antagonistic bacterium with high antibacterial activity against many pathogens. Fermentation medium for the production of the antibacterial substances was statistically optimized by Plackett-Burman design, steepest ascent experiments and response surface methodology. The optimized medium was composed of (g/L): glucose 15.6, soybean meal 28.4, starch 6, CaCO3 2 and MgSO4 4. After optimization, the production of antibacterial metabolites increased more than 70% than that of control.

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Periodical:

Edited by:

J.L. Zhong

Pages:

355-360

DOI:

10.4028/www.scientific.net/AMR.345.355

Citation:

Z. Song et al., "Medium Optimization for the Antibacterial Substances Production from Brevibacillus brevis XDH Using Response Surface Methodology", Advanced Materials Research, Vol. 345, pp. 355-360, 2012

Online since:

September 2011

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Price:

$35.00

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