Based on the depositional model and characteristics of fan delta, the short-term base-level cycle of the third submember of the third member of Shahejie Formation （Es33）in North region major oil layer of Liuzan Oilfield of Nanpu Sag is divided into three basic categories applying high-resolution sequence stratigraphy with the reference to core and logging data, namely, deepening-upward asymmetrical type, shallowing-upward asymmetrical type and symmetrical type. Different variation models for macroscopic heterogeneity of reservoir belonging to different categories of short-term base-level cycle were established in this paper; it was further pointed out that the changes of base-level and the ancient landform were major factors controlling the characteristic discrepancy of macroscopic heterogeneity of reservoir. In fan delta plain area, the ancient landform is smooth. Deepening-upward asymmetrical cycle is mainly composed of braided river sand body, and the changes of base-level exert little control on porosity with significant control on permeability. At the delta front slope, the landform becomes steep. Deepening-upward asymmetrical cycle is mainly composed of underwater distributary channel with genetic mechanism of gravity flow. The vertical variations of porosity and permeability inside the cycle are rather complicated. Since the physical properties are mainly manifested as the control on autogenic cycle, they do not directly influence the changes of base level.