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Extraction of Gatifloxacin in Water by Use of Ionic Liquid–Salt Aqueous Two-Phase System
Abstract:
An ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate( [BMIM] BF4) / salt aqueous two-phase systems (ATPS) was presented as a simple, rapid and effective sample pretreatment technique coupled with double-beam UV-Vis spectrophotometer for analysis of gatifloxacin in water. For the purpose to choose optimal conditions, various factors were considered systematically, and the results indicated that the pH value, the salt-out ability of salt and the amount of [BMIM] BF4 had great influence on phase separation and extraction. Under the optimal condition, gatifloxacin in different concentration were enriched and determined, the recovery was 87.3–91.5%.
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195-198
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October 2011
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© 2012 Trans Tech Publications Ltd. All Rights Reserved
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