The growth pole theory has a very important role in regional economic development. The theory was introduced to analyze spatial structure evolvement of coastal tourism region in Liaoning province which includes six cities: Dalian, Dandong, Panjin, Jinzhou, Yingkou and Huludao. And the tourism industry location quotient model was defined and was used to select the growth poles at city scale and tourist attractions scale of tourism industry based on relevant statistical data. The results showed that the cities of Dalian and Dandong can be treated as the first level growth poles at city scale, which the second level includes Huludao and Jinzhou, and the third level includes Panjin and Yingkou. And the growth poles at tourist attraction scale were established too. All the growth poles were incorporated with the coastal road to make up the pole-axis system, and then countermeasures were proposed for rational development of tourism industry of coastal tourism region in Liaoning Province.