Following with the rapid urbanization and industrialization, there are more and more relatively specific functional areas integrated by some function units such as industrial areas, residential areas, campuses, commercial areas and so on. Due to involving many functional units, the safety risk of the SFA becomes increasingly prominent and safety management problems have drawn the wide concerns of city managers, experts and scholars. The paper puts forward the conception of building the integration mechanism of safety management in urban SFA through analyzing the backgrounds of urban specific functional areas and its safety management situation. It clarifies the contents of the integration mechanism of safety management in urban specific functional areas from the aspects of security information platform, security publicity and education, security cultural patterns, security management systems, safety supervision, resource integration and sharing, puts forward some suggestions about safety management of specific functional areas. It will offer the theoretical reference for the making the security management plan of urban specific functional areas, urban public security planning, the division of urban functional areas, and the layout of industries.