Boron Trifluoride Etherate - A Mild and Inexpensive Reagent for Synthesis of Coumarin Derivatives under Solvent-Free Conditions
Coumarins are important structural units of many natural product, and feature widely in pharmacologically and biologically active compounds. Now, a mild and convenient synthesis of coumarins catalyzed by boron trifluoride etherate is reported in this study with up to 98% isolated yield.
G. J. Sun et al., "Boron Trifluoride Etherate - A Mild and Inexpensive Reagent for Synthesis of Coumarin Derivatives under Solvent-Free Conditions", Advanced Materials Research, Vol. 365, pp. 228-232, 2012