High-Sealing Microvalves for PCR

Xue Ting Li; An Qun Wang

doi:10.4028/www.scientific.net/AMR.383-390.2025

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 383-390High-Sealing Microvalves for PCR

High-Sealing Microvalves for PCR

Abstract:

This paper reviews several suitable microvalves for polymerase chain reaction (PCR). First, three type micro-valves in PCR chips are discussed, including pneumatic, servomotor-controlled and passive plug microvalves. Then we present our servomotor-controlled microvalves, with the structure of long passive plug. This valve had many obvious advantages such as simple fabrication and operation, perfect sealing, the ability to withstand relatively high pressure. Furthermore, the microvalve can be operated in a self-actuated mode.

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Manufacturing Science and Technology, ICMST2011

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Periodical:

Advanced Materials Research (Volumes 383-390)

Pages:

2025-2030

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.383-390.2025

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Online since:

November 2011

Authors:

Xue Ting Li, An Qun Wang

Keywords:

High-Pressure, Microvalve, Passive Plug, Pneumatic, Polymerase Chain Reaction (PCR), Servomotor-Controlled

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