Predict Interactions between Protein Residues for Developing Antibody Therapeutics

Abstract:

Article Preview

Recently, protein-antibody therapeutics becomes a hot search topic. In this paper, all protein interaction data files are collected from INTERPARE. Protein sequence and its secondary structure both are used to build HMM mathematical model. We randomly take 80% data to train positive and negative HMM models and 20% data to test. The accuracy of this approach can reach to 79.80%. This model can further be used to predict protein function sites and predict if a protein interacts with other proteins.

Info:

Periodical:

Advanced Materials Research (Volumes 383-390)

Edited by:

Wu Fan

Pages:

4003-4006

DOI:

10.4028/www.scientific.net/AMR.383-390.4003

Citation:

W. L. Shu and C. H. Lee, "Predict Interactions between Protein Residues for Developing Antibody Therapeutics", Advanced Materials Research, Vols. 383-390, pp. 4003-4006, 2012

Online since:

November 2011

Export:

Price:

$35.00

In order to see related information, you need to Login.

In order to see related information, you need to Login.