A Colorific and Fluorescent Dual Signal Probe for DNA

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The synthesis and characteristics of a new styryl colorific and fluorescent dual signal probe for DNA are described. Sty-HPy shows a high fluorescence enhancement (> 35-fold) in conjunction with a visible colorific change (45 nm red-shift) when bound to dsDNA. The large Stokes shift (140 nm) and sensitive colorific response to DNA are both attributed to the rational design of intramolecular charge transfer (ICT) intra Sty-HPy.

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398-402

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January 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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