Research on Inorganic Medical Capsule Derived from Novel Emulsion Route

Article Preview

Abstract:

Hydrochloric acid was directly adopted as water phase and catalyst to prepare the silica shell, hexane and Span 80 were respectively adopted as oil phase and emulsifier to prepare water-in-oil (W/O) emulsion. TEOS was adopted as the silica source, then the silica shell can be obtained through the sol-gel route at the interface of emulsion. The SiO2 inorganic medical capsule was obtained, and the morphology of samples experience from irregular to regular with the increase of both water phase and stirring rate. Stability of emulsion can greatly affect the morphology of capsule. Control of ratio of water phase to oil phase is vital to the formation of SiO2 inorganic medical capsule. Furthermore, schematic transformation model of emulsion droplet under different conditions was proposed.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

356-359

Citation:

Online since:

January 2012

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2012 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] M.S. Romero-Cano and B. Vincent: J. Control. Release Vol. 82 (2002), p.127.

Google Scholar

[2] M. Changez, K. Burugapalli, V. Koul and V. Choudhary: Biomaterials Vol. 24 (2003), p.527.

Google Scholar

[3] Soo-Jin Choi, Jae-Min OH and Jin-Ho Choy: Journal of the Ceramic Society of Japan, Vol. 117 (2009), p.543.

Google Scholar

[4] Z.Z. Li, S.A. Xu, L.X. Wen, F. Liu, A.Q. Liu, Q. Wang, H.Y. Sun, W. Yu and J.F. Chen: J. Control. Release Vol. 111 (2006), p.81.

Google Scholar

[5] J.F. Chen, H.M. Ding, J.X. Wang and L. Shao: Biomaterials Vol. 25 (2004), p.723.

Google Scholar

[6] J.X. Wang, Z.H. Wang, J.F. Chen, J. Yun: Material Research Bulltin, Vol. 43 (2008), p.3374.

Google Scholar