Assess the Effect of the Foot and Mouth Disease Type O Inactivated Vaccine (O/MYA98/BY/2010 Strain) for Pigs

Article Preview

Abstract:

Recently, O-type foot and mouth disease epidemic situation has changed, there has been MYA98 epidemic strains, has caused many Asian countries for many kinds of animal damage. In January 2011, a new matching vaccine developed, namely Foot and mouth disease type O inactivated vaccine (O/MYA98/BY/2010 strain). In order to master this vaccine effectiveness in pig production, all the individual pigs in the ten farms had been immunized.A total of 97786 individuals or times immunized pigs were observed. All pigs were traced surveillance for foot and mouth clinical signs. A total of 295 serum samples were detected for antibody titers.The results show that although there adverse side effects, but other than the vaccine adverse reactions and extent has significantly decreased, pigs immunized were non-occurrence of type O foot and mouth disease, the antibody titer is eligible. So here we show , the vaccine is safe and effective, can be widely used.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 468-471)

Pages:

365-369

Citation:

Online since:

February 2012

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2012 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] OIE Terrestrial Manual 2009 on http:// www. oie. int/animal health in the world/fmd portal/prevention and control.

Google Scholar

[2] 2011 © OIE - Terrestrial Animal Health Code on http: // www. oie. int/animal health in the world/fmd portal/prevention and control/

Google Scholar

[3] United States Department of Agriculture, FAD PReP/NAHEMS Guidelines: Vaccination for Foot-and-Mouth Disease, 2011 [http: // www. cfsph. iastate. edu/pdf/fad prep nahems guidelines vaccination for contagious diseases]

Google Scholar

[4] Kitching RP,Global epidemiology and prospects for control of foot-and-mouth disease. Curr Top Microbiol Immunol. 288 (2005) 133-48.

Google Scholar

[5] Gay CG, Charleston B, Carrillo E, Dubourget P, Duffy S et al, National Veterinary Stockpile (NVS) Countermeasures Working Group report. Foot-and-mouth disease. NVS, 2007. [http: //www. foot-andmouth. org/fmd csf ca/community/work-package 1-research/ APPENDIX%204%20NVS%20 20CSF%20Countermeasures%20Group%20Expert%20Report. pdf/at download/file]. (Accessed 6 Mar 2010).

Google Scholar

[6] Robiolo B, La Torre J, Maradei E, Beascoechea CP, Perez A, Seki C, Smitsaart E, Fondevila N,Palma E, Goris N, De Clercq K, Mattion N. Confidence in indirect assessment of foot-and-mouth disease vaccine potency and vaccine matching carried out by liquid phase ELISA and virus neutralization tests. Vaccine. 2010;28(38):6235-41.FAD PReP/NAHEMS Guidelines: Vaccination for Foot-and-Mouth Disease (2011) 77

DOI: 10.1016/j.vaccine.2010.07.012

Google Scholar

[7] Grein K, Papadopoulos O, Tollis M. Safe use of vaccines and vaccine compliance with food safety requirements. Rev Sci Tech. 2007;26(2):339-50.

Google Scholar

[8] Eblé PL, Bouma A, de Bruin MG, van Hemert-Kluitenberg F, van Oirschot JT, Dekker A.Vaccination of pigs two weeks before infection significantly reduces transmission of foot-andmouth disease virus. Vaccine. 2004; 22(11-12):1372-8.

DOI: 10.1016/j.vaccine.2003.11.003

Google Scholar

[9] Eblé PL, de Bruin MG, Bouma A, van Hemert-Kluitenberg F, Dekker A. Comparison of immune responses after intra-typic heterologous and homologous vaccination against foot-and-mouth disease virus infection in pigs. Vaccine. 2006; 24(9):1274-81.

DOI: 10.1016/j.vaccine.2005.09.040

Google Scholar

[10] Parida S, Fleming L, Oh Y, Mahapatra M, Hamblin P, Gloster J, Doel C, Gubbins S, Paton DJ.Reduction of foot-and-mouth disease (FMD) virus load in nasal excretions, saliva and exhaled air of vaccinated pigs following direct contact challenge. Vaccine. 2007;25(45):7806-17.

DOI: 10.1016/j.vaccine.2007.08.058

Google Scholar

[11] Golde WT, Pacheco JM, Duque H, Doel T, Penfold B, Ferman GS, Gregg DR, Rodriguez LL.Vaccination against foot-and-mouth disease virus confers complete clinical protection in 7 days and partial protection in 4 days: Use in emergency outbreak response. Vaccine.2005;23(50):5775-82.

DOI: 10.1016/j.vaccine.2005.07.043

Google Scholar

[12] Doel TR, Williams L, Barnett PV. Emergency vaccination against foot-and-mouth disease: rate of development of immunity and its implication for the carrier state. Vaccine. 1994;12:592–600

DOI: 10.1016/0264-410x(94)90262-3

Google Scholar

[13] Donaldson AI, Kitching RP. Transmission of foot-and-mouth disease by vaccinated cattle following natural challenge. Res Vet Sci. 1989; 46(1):9-14.

DOI: 10.1016/s0034-5288(18)31109-3

Google Scholar

[14] Cox SJ, Parida S, Voyce C, Reid SM, Hamblin PA, Hutchings G, Paton DJ, Barnett PV. Further evaluation of higher potency vaccines for early protection of cattle against FMDV direct contact challenge. Vaccine. 2007;25(44):7687-95.

DOI: 10.1016/j.vaccine.2007.07.067

Google Scholar

[15] Goris N, Merkelbach-Peters P, Diev VI, Verloo D, Zakharov VM, Kraft HP, De Clercq K. European Pharmacopoeia foot-and-mouth disease vaccine potency testing in cattle: between test variability and its consequences. Vaccine. 2007;25(17):3373–9.

DOI: 10.1016/j.vaccine.2006.12.049

Google Scholar