Synthesis and Characteristic of Molecularly Imprinted Polymer Immobilized Mesoporous Silica Sphere for Selective Binding of S-Naproxen

Abstract:

Article Preview

Molecularly imprinted composite materials (PM) selective to S-naproxen were prepared in the surface of mesoporous silica sphere (SBA-15) by surface imprinting technique. FT-IR, SEM and surface area analysis were used to study the structural morphology of PM and MIPs particles and probe the incorporation of polymer into the SBA-15 framework. The results revealed that PM showed better binding affinity and selectivity to the template molecule than MIPs and the maximum saturated binding capacity of PM to S-naproxen and R-naproxen was about 10.3332 and 6.0063µmol·g-1. Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications such as chromatographic stationary phases for chiral separations.

Info:

Periodical:

Advanced Materials Research (Volumes 47-50)

Edited by:

Alan K.T. Lau, J. Lu, Vijay K. Varadan, F.K. Chang, J.P. Tu and P.M. Lam

Pages:

890-893

DOI:

10.4028/www.scientific.net/AMR.47-50.890

Citation:

N. C. Bing et al., "Synthesis and Characteristic of Molecularly Imprinted Polymer Immobilized Mesoporous Silica Sphere for Selective Binding of S-Naproxen", Advanced Materials Research, Vols. 47-50, pp. 890-893, 2008

Online since:

June 2008

Export:

Price:

$35.00

In order to see related information, you need to Login.