Preparation of the Amphiphilic Copolymer of Poly(ethyleneoxid-co-glycidol)-Graft-Poly(lactide) and their Extraction for Dyes

Abstract:

A well-defined graft copolymer poly(ethylene oxide-co-glycidol)-graft-Poly(lactide) [poly(EO-co-Gly)-g-PLA] of poly(ethylene oxide-co-glycidol) [(poly(EO-co-Gly)] as main chain and poly(lactide) (PLA) as the side chain was successfully prepared via combination of anionic polymerization and ring-opening polymerization. The glycidol was protected by ethyl vinyl ether first to form 2, 3-epoxypropyl-1-ethoxyethyl ether (EPEE), and then copolymerized with EO by initiation with the mixture of diphenylmethylpotassium and triethylene glycol to obtain the well-defined poly(EO-co-EPEE). The latter was hydrolyzed in the acidic conditions and then coordination-insertion ring-opening polymerization of lactide(LA) with poly(EO-co-Gly) was completed. The object products and intermediates were characterized by 1HNMR, MALDI-TOF-MS and GPC in detail. The experimental results confirmed that poly(EO-co-Gly)-g-PLA showed strong conjugation ability with the dyes.

• Periodical: Advanced Materials Research (Volumes 482-484)
• Pages: 1912-1916
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.482-484.1912
• Online since: February 2012
• Authors: Xin Zhao, Kun Yan Sui, Hong Chao Liang, Yu Jin Li, Yang Zhang, Yan Zhi Xia
• Keywords: Anionic Polymerization, Graft Copolymer, Poly (Ethylene Oxide), Poly(lactide), Ring-Opening Polymerization

References

[1] Y. Ren, G.W. Wang and J.L. Huang. Biomacromolecules 8 (2007), 1873.

[2] J.H. De Groot, F.M. Zijlstra, H.W. Kuijpers, A.J. Pennings, J. Klompmaker, R. P. H. Veth, H.W.B. Jansent. Biomaterial 18 (1997), 613.

[3] M. Vert, S.M. Li, G. Guerin, P. J Mater Sci Mater Med 3 (1992), 432.

[4] H. Peng, X.L. Mao, R. Crawford, K.A. Whittaker. Biomacromolecules 10 (2009), 95.

[5] M.T. Peracchia, R. Gref, N. Lotan, Robert. Langer. J Controlled Release 46 (1997), 223.

[6] A.C. Albertsson, K.I. Varma. Biomacromolecules 4 (2003), 1466.

[7] S.B. Zhou, Deng, X. M.; Yang, H. Biomaterials 24 (2003), 3563.

[8] Z.Y. Li, P.P. Li, J.L. Huang. J Polym. Sci. Part A Polym. Chem 44 (2006), 4361.

[9] Z.Y. Li, P.P. Li, J.L. Huang. Polymer 47 (2006), 5791.

[10] K. Tamano, T. Imae, S. Yusa, Y. Shimada. J Phys Chem B 109 (2005), 1226.

[11] X.C. Pang, G.W. Wang, J.L. Huang. J Polym Sci Part A: Polym Chem 45 (2007), 5824.

[12] C.H. Liu, C. Gao, D.Y. Yan. Macromolecules 39 (2006), 8102.