The Establishing and Applied Research of Animal Models of Mammary Precancerous Lesions

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Abstract:

Currently, the methods of establishing mammary precancer animal model is various, including hormones-induced precancerous lesions model, chemical carcinogen precancerous lesions model, precancerous lesions model induced by hormones combined with chemical carcinogen, MCF10AT cell lines transplantation model, transgenic model and disease and syndrome animal model. This paper aims to explore the establishing and applied research of animal models of mammary precancerous lesions. Showing it would play a critical role in studying the cause and pathogenesis of mammary precancerous lesions, effective prevention and improving treatment effect by a proper mammary precancerous lesion animal model.

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Advanced Materials Research (Volumes 554-556)

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1725-1729

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July 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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