Metabonomic Investigation on Rats’ Dynamic Responses to Cantonese Herbal Tea Intake

Rong You; Zhen Bo Xu; Bing Li; Lin Li

doi:10.4028/www.scientific.net/AMR.554-556.1742

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 554-556Metabonomic Investigation on Rats’ Dynamic...

Metabonomic Investigation on Rats’ Dynamic Responses to Cantonese Herbal Tea Intake

Abstract:

GC-MS-based metabonomics was applied to investigate the urinary metabolic response to Cantonese Herbal tea (CHT) intake during a 38-day-period. Orthogonal projection on latent structures discriminant analysis (OPLS-DA) with student’s t-test revealed that the global characterization of metabolic changes at each sampling time point were different. Dynamic sampling made it possible to evaluate dynamic metabolic responses to CHT intake.

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Advanced Materials Research (Volumes 554-556)

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1742-1746

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https://doi.org/10.4028/www.scientific.net/AMR.554-556.1742

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July 2012

Authors:

Rong You, Zhen Bo Xu, Bing Li, Lin Li

Keywords:

Cantonese Herbal Tea, Dynamic Sampling, Metabonomics, OPLS-DA

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References

[1] Craig, W., Health-promoting properties of common herbs. American Journal of Clinical Nutrition, 1999. 70(3): p. 491S.

DOI: 10.1093/ajcn/70.3.491s

Google Scholar

[2] He, R.R., et al., The Anti-stress Effects of Guangdong Herbal Tea on Immunocompromise in Mice Loaded with Restraint Stress. Journal of Health Science, 2011. 57(3): pp.255-263.

DOI: 10.1248/jhs.57.255

Google Scholar

[3] Nicholson, J.K. and J.C. Lindon, Systems biology: metabonomics. Nature, 2008. 455(7216): pp.1054-1056.

DOI: 10.1038/4551054a

Google Scholar

[4] Qiu, Y., et al., Urinary Metabonomic Study on Colorectal Cancer. J. Proteome Res, 2010. 9(3): pp.1627-1634.

Google Scholar

[5] Wang, Y., et al., Global metabolic responses of mice to Trypanosoma brucei brucei infection. Proceedings of the National Academy of Sciences, 2008. 105(16): p.6127.

DOI: 10.1073/pnas.0801777105

Google Scholar

[6] Brindle, J., et al., Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1 H-NMR-based metabonomics. Nature Medicine, 2002. 8(12): pp.1439-1445.

DOI: 10.1038/nm1202-802

Google Scholar

[7] Bjerrum, J., et al., Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology. J Proteome Res, 2010. 9(2): pp.954-962.

DOI: 10.1021/pr9008223

Google Scholar

[8] kinross, J., et al., Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. Journal of proteome research, 2011(10): pp.277-287.

DOI: 10.1021/pr1003278

Google Scholar

[9] Morvan, D. and A. Demidem, Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloroethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways. Cancer research, 2007. 67(5): p.2150.

DOI: 10.1158/0008-5472.can-06-2346

Google Scholar

[10] Lindon, J., E. Holmes, and J. Nicholson, Metabonomics in pharmaceutical R & D. FEBS journal, 2007. 274(5): pp.1140-1151.

DOI: 10.1111/j.1742-4658.2007.05673.x

Google Scholar

[11] Solanky, K., et al., Biofluid 1H NMR-based metabonomic techniques in nutrition research——metabolic effects of dietary isoflavones in humans. The Journal of Nutritional Biochemistry, 2005. 16(4): pp.236-244.

DOI: 10.1016/j.jnutbio.2004.12.005

Google Scholar

[12] You, R., et al., Characterization of Temporary Metabolic Changes Following Cantonese Herbal Tea Intervention. Phytotherapy Research, 2012.

DOI: 10.1002/ptr.3674

Google Scholar

[13] Smith, C., et al., XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Analytical chemistry, 2006. 78(3): pp.779-787.

DOI: 10.1021/ac051437y

Google Scholar

[14] Wikoff, W.R., et al., Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. Journal of proteome research, 2009. 8(7): pp.3578-3587.

DOI: 10.1021/pr900275p

Google Scholar