Simulation of Vacuum Rotating Dryer to Dry Caffeine Colloid

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Abstract:

It is time-consuming to dry the caffeine colloid got from caffeine methylation liquid after evaporating crystallization and cooling crystallization. To solve this problem, the laboratory equipment is designed to simulate vacuum rotating dryer to dry the caffeine colloid. Through the single-factor experiment and orthogonal experiment, the suitable dry conditions are determined as follows: the heating temperature is 110 °C; the vacuum degree is 0.09 MPa; the stirring speed is 250 rpm. The drying time under the optimal process conditions is reduced to 1.01hours.

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Advanced Materials Research (Volumes 560-561)

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1159-1164

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August 2012

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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[1] Z.C. Huang, Z.W. Liu, Study on Synthetic Unit Reaction and Methods of Caffeine, Chem. Prod. Tech. 6 (1999) 27-32.

Google Scholar

[2] X.E. Hu, W.Z. Dai, X.J. Wang, Z.J. Guo, B.Q. Liao, R.S. Bai, Study of Extraction Process of Caffeine by Chloroform, J. Tsinghua. Unives. (Sci. Tech). 35 (1995) 13-19.

Google Scholar

[3] Z.Y. Zhu, Z.Z. Lv, Y.L. Wang, J. Gao, P.Z Cui, Measurement and Correlation for Solubility of Sodium Methyl Sulfate in Water, Ethanol, Chloroform and Cyclohexane, unpublished.

Google Scholar

[4] D. Skansi, S. Tomas, I. Fudic, A. Arapovic, The influence of pressure and temperature on the kinetics of vacuum drying of ketoprofen, Dry. Technol. 15 (1997) 1617–1631.

DOI: 10.1080/07373939708917312

Google Scholar

[5] A. Lekhal, K.P. Girard, M.A. Brown, S. Kiang, J.G. Khinast, B.J. Glasser, The effect of agitated drying on the morphology of L-threonine (needle-like) crystals, Int. J. Pharmaceut. 270 (2004) 263–277.

DOI: 10.1016/j.ijpharm.2003.10.022

Google Scholar

[6] C.H. Xu, Z.J. Zhang, S.W. Zhang, R.L. Peng, B. Zhang, Analysis of Status Quo and Development Trend Vacuum Drying, Dry. Tech. Eq. 7 (2009) 207-213.

Google Scholar

[7] A. Erriguible, P. Brnada, F. Couture, M.A. Roques, Simulation of vacuum drying by coupling models, Chem. Eng. Proc. 46 (2007) 1274-1285.

DOI: 10.1016/j.cep.2006.10.011

Google Scholar

[8] M. Kohout, F. Stepanek, Multri-scal Analysis of Vaccum Contact Drying, Dry. Technol. 25 (2007) 1265-1273.

Google Scholar

[9] H.J.M. Slangen, The need for fundamental research on drying as perceived by the European chemical industry, Dry. Technol. 18 (2000) 1601–1604.

DOI: 10.1080/07373930008917795

Google Scholar