Ultrasound-Aided Fabrication of Carbonated Silicon-Substituted HA Nanopowder and its Configuration Characterization

Abstract:

Two inorganic compounds containing CO32- and SiO44- groups were introduced and ultrasound-aided coprecipitation method was applied to fabricate carbonated silicon-substituted hydroxyapatite (CSi-HA) nanopowder. The synthetic process was optimized and the crystalline phase, grain dimension and morphology of the CSi-HA nanopowder were characterized. The obtained results demonstrate that H3PO4 addition into alkaline Ca(OH)2 ammonia liquid with ultrasonic application can obviously prevent secondary phase formation and make the nascent HA product pure, highly dispersed and gel-like. The introduction of Na2SiO3 and Na2CO3 mixed solution as doping source into the nascent HA product with also continuous ultrasound utilization can effectively realize the ionic group substitution of HA by CO32- and SiO44- and make the final CSi-HA nanopowder fine and uniform. It was also found that the CSi-HA grain size shows a decrease trend with the increase of CO32- and SiO44- substitution in the experimental range.

• Periodical: Advanced Materials Research (Volumes 560-561)
• Pages: 714-721
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.560-561.714
• Online since: August 2012
• Authors: Chao Wu Zhang, Chang Tao Liu, Ling Xiao, Fen Wang, Cong Yue Duan
• Keywords: Carbonated, Configuration Characterization, Silicon-Substituted Hydroxyapatite, Ultrasonic Coprecipitation

References

[1] E. S. Thian, J. Huang, S. M. Best, et al. Silicon-substituted hydroxyapatite: The next generation of bioactive coatings , J. Mater Sci Eng, C27(2) (2007) 251-256.

DOI: 10.1016/j.msec.2006.05.016

[2] N. Pater, S. M. Best, M. A. Lopes, I. R. Gibson. Structurual analysis of Si-substituted hydroxyapatite: zeta potential and X-ray photoelection spectroscopy, J. Mater Sci mater med, 13(2002)1123-1127.

[3] F. Balas, J. Perez-Pariente, M. Vallet-Regy. In vitro bioactivity of silicon-substituted hydroxyapatites, J. J Biomed Mater Res, 67A(2) (2003)364-375.

DOI: 10.1002/jbm.a.10579

[4] D. Arcos, J. Rodriguez-Carvajal, M. Vallet-Regi. Silicon incorporation in hydroxyapatite obtained by controlled crystallization, J. Chem. Mater, 16(6) (2004)2300-2308.

DOI: 10.1021/cm035337p

[5] ZHANG Chaowu, ZHOU Fangyuan, WANG Fen, YANG Jun, XIAO Ling. Ultrasonic Co-deposit Fabrication of Si-HA Nanopowder and Mechanical Property of Its Bio-cement, J. Materials Review, 24(11) (2010)42-45.

[6] B. R. Constantz, I. C. Ison, M.T. Fulmer, et al. Skeletal repair by in situ formation of the mineral phase of bone, J. Science, 267 (5205) (1995)1796-1799.

DOI: 10.1126/science.7892603

[7] YAO Qi, TANG Peifu, HUANG Peng, WANG Jifang. Importance of Carbonate Group in Hydroxyapatite Cement and Its Compatibility with Bone Tissue, J. Functional Materials, 38(2) (2007) 819-822.