Study on the Thermodynamic Properties of Two Anti-Cancer Drugs

W. W. Zhao; J. Q. Gao; D. H. Liu; Z. X. Li

doi:10.4028/www.scientific.net/AMR.634-638.1086

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Study on the Thermodynamic Properties of Two Anti-Cancer Drugs
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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 634-638Study on the Thermodynamic Properties of Two...

Study on the Thermodynamic Properties of Two Anti-Cancer Drugs

Abstract:

The dissolution enthalpy of Cisplatin and Etoposide in the appropriate solvent were measured by RD496-2000 microcalorimeter under the conditions of atmospheric pressure and 309.65 K. The differential heat and the integral heat of the process are obtained, thereby establishing the relationship between the heat and the amount of solute, knowing that the dissolution process is the pseudo-first order reaction. In turn, the half-life, △solHm, △solGm, △solSm are also can obtained.