The Synthesis and Bioactivities of 2-Hydroxyethyl Benzo[d] Isothiazole-3(2H)-One Marine Antifouling Paints

Abstract:

Twenty-one novel compounds were synthesized from the benzo[d]isothiazole-3(2H)-one and aromatic acid, the structures were identified by means of 1H NMR, IR, EA. The intro antibacterial experiment was carried out to evaluate the activities against antibacterial and the marine hanging plate experiment was also carried out to evaluate the activities against marine fouling organism. The results showed that all the compounds were active against the six bacterials, with an inhibiting rate of 90% at the concentration of 32 µg/ml against Gram-positive bacterials, and the antifouling paints couldn’t be attached by marine fouling organisms in the marine environment for more than 3 months.

• Periodical: Advanced Materials Research (Volume 646)
• Pages: 24-29
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.646.24
• Online since: January 2013
• Authors: Jian Xin Yang, Cheng Hang You, Xiang Hui Wang, Qiang Lin
• Keywords: Antibacterial, Antifouling Paints, Aromatic Acid Esters, Benzo[d]isothiazole-3(2H)-One

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