Chemical Constituents and Cytotoxic Activity of Gentiana farreri Balf.f.

Ai Mei Yang; Hui Li; Jing Sun; Rui Wu; Wei Jie Guo

doi:10.4028/www.scientific.net/AMR.655-657.1945

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 655-657Chemical Constituents and Cytotoxic Activity of...

Chemical Constituents and Cytotoxic Activity of Gentiana farreri Balf.f.

Abstract:

Six compounds were isolated from Gentiana farrerii, which was used as traditonal herb medicine in the treatment of some diseases. Their structures were identified as: linoleic acid(1), dibutyl-phthalate(2), p-hydroxy benzaldehyde (3), hydroxyacetophenone (4), isoscoparin (5), 5,7,3',4'-tetrahydroxyflavone-6--D-glucopyranoside(6). All compounds were isolated from Gentiana farrerii for the first time. The cytotoxic activity on the growth of HepG-2 cells of all compounds were investigated in MTT assay, the results showed that compound 2, 5, 6 have weak cytotoxic activity, IC50 is 41.26, 96.74, 99.33 (μg/ml), respectively.

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Advanced Materials Research (Volumes 655-657)

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1945-1948

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https://doi.org/10.4028/www.scientific.net/AMR.655-657.1945

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January 2013

Authors:

Ai Mei Yang, Hui Li, Jing Sun, Rui Wu, Wei Jie Guo

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Chemical Constituents, Cytotoxic Activity, Gentiana farreri Balf.f.

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