SO3H-Functionalized Ionic Liquids-Catalyzed Facile and Efficient Procedure for Fischer Indole Synthesis under Ultrasound Irradiation

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A facile and efficient synthesis of indole has been developed using ketones or cyclohexandiones with aryhydrazine hydrochlorides in 85% to 95% yields in water under ultrasound irradiation in the presence of Novel SO3H-functionalized ionic liquids (ILs) catalyst. Simple work-up procedure, environmentally friendly, inexpensive and non-toxic catalyst, shorter reaction times along with excellent product yields are the significant features of this practical method.

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150-153

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February 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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