Immunomodulatory Activity in Vivo of Porcine Cartilage Polysaccharide Nanoparticles on Murine H22 Hepatocarcinoma Cells

Jing Jing Fang; Zhen Yuan Zhu; An Guo Teng; Guo Qiang Zheng; Wen Hang Wang; Jie Zheng; An Jun Liu

doi:10.4028/www.scientific.net/AMR.690-693.1208

Paper Titles

Asymmetric Synthesis of Ethyl (R)-4-Chloro-3-Hydroxybutanoate with a Two Recombinant Escherichia coli System
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Comparison of the Roles of Tea Polysaccharides and Polyphenols in Growth Inhibition of Hepatoma H22 Cells in Mice
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Effects of the Protein in Wheat Straw on Enzymatic Hydrolysis
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Enzymolysis Optimization of Walnut Residue Protein Using Trypsase
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Immunomodulatory Activity in Vivo of Porcine Cartilage Polysaccharide Nanoparticles on Murine H₂₂ Hepatocarcinoma Cells
p.1208

Influence of Cortical Layer Thickness of Alveolar Bone on Stress Distribution over Implant Supported Region
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Kinetics Study of Vitamin A Precursor Synthesis by Immobilized Lipase-Catalyzed Regioselective Monoacetylation in n-Hexane
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Mechanism of Peptide Changes during Drying Fermented Soybean Meal
p.1224

Numerical Simulation of Cell Growth Pattern and Determination of Fractal Dimension of Cell Cluster
p.1229

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Immunomodulatory Activity in Vivo of Porcine Cartilage Polysaccharide Nanoparticles on Murine H₂₂ Hepatocarcinoma Cells

Abstract:

The immunostimulatory activity of porcine cartilage polysaccharide nanoparticles was evaluated by using in vivo animal models. The results demonstrated that porcine cartilage polysaccharide nanoparticles not only signiﬁcantly prolonged the survival period in H₂₂ tumor-bearing mice and inhibiting H₂₂ cells proliferation, but also remarkably increased the spleen index and thymus index. These results suggest that porcine cartilage polysaccharide nanoparticles might be a strong natural immunomodulator and the antitumor effect of these nanoparticles is associated with its potent immunostimulating effect.