Study on the Function of miRNA-155 Target Using Bioinformatics Methods

De Ming Han; Zi Jun Shen; Li Hui Zhao

doi:10.4028/www.scientific.net/AMR.709.858

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 709Study on the Function of miRNA-155 Target Using...

Study on the Function of miRNA-155 Target Using Bioinformatics Methods

Abstract:

MicroRNAs are small non-coding RNAs that act at the post-transcriptional level, regulating protein expression by repressing translation or destabilizing mRNA target. We searched information about miR-155 in miRBase. Target genes of miR-155 are predicted by four miRNA target gene prediction softwares. The result shows that miR-155 was involved in proliferation, differentiation and apoptosis. These results can contribute to further study on the role of microRNA in diagnosis and treatment of cancer.

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Periodical:

Advanced Materials Research (Volume 709)

Pages:

858-861

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.709.858

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Online since:

June 2013

Authors:

De Ming Han, Zi Jun Shen, Li Hui Zhao

Keywords:

Bioinformatics, MiR-155, Target Gene

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