Preparation of ε-Polylysine Modified Silica Nanoparticles

Zhi Lei Tan; Bei Xing; Shi Ru Jia; Fang Lian Yao

doi:10.4028/www.scientific.net/AMR.712-715.511

Paper Titles

Rapid Identification of Microorganisms Isolated from Pickled Vegetables by MALDI-TOF Mass Spectrometry
p.494

Assessment on Pollution Level and Ecological Risk of Heavy Metals in Pond Sediment of Suburban District
p.498

The Preparation of Micro-Molecular Dextran in Sub-Critical Water/CO₂
p.502

Supercritical Carbon Dioxide Extraction of the Fatty Acids from Pacific white Shrimp Waste (Litopenaeus vannamei)
p.506

Preparation of ε-Polylysine Modified Silica Nanoparticles
p.511

Screening of Biosurfactant-Producing Bacteria
p.515

Time Change Rule and Source Identification of Nitrogen and Phosphorus Pollution on Huihe River in Suzhou City
p.520

Adsorption of Cr Ion by Activated Carbon Prepared from Corncob Xylitol Residue
p.527

Adsorption of Corncob Hydrolysis Residue on Cr (VI)
p.531

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 712-715Preparation of ε-Polylysine Modified Silica...

Preparation of ε-Polylysine Modified Silica Nanoparticles

Abstract:

Gene vector system is the key to realize gene transduction and therapy. A proper gene vector can introduce the target gene into cells securely, efficiently, controllably and easily, and achieve purposes of gene transfection and disease treatment after its expression. ε-polylysine (ε-PL),which is rich in cationic and has high penetrability through biological membrane,can be applied in DNA carrier. In this study, we presented a novel approach for preparing ε-polylysine modified silica nanoparticles and combinating them with plasmid DNA.