Preparation of Interface-Cross-Linked Micelles as Drug Delivery via RAFT Polymerization

Jian Ping Li; Lian Lai Cui; Xin Tan; Ling Zhang

doi:10.4028/www.scientific.net/AMR.716.147

Paper Titles

Evaluation of Various Laminated Plate Theories Accounting for Interlaminar Transverse Shear Stress Continuity
p.119

Surface Charge Research of Graphene Oxide, Chemically Reduced Graphene Oxide and Thermally Exfoliated Graphene Oxide
p.127

Microstructural Characteristics of Multiphase Low Carbon Steel Welds with Different Ti and B Element Contents
p.132

Electrochemical Investigations on Structures of Flexible Textile Electrodes
p.138

Preparation of Interface-Cross-Linked Micelles as Drug Delivery via RAFT Polymerization
p.147

Microstructure and Growth Mechanism of Glucose-Carburized Nickel Substrates
p.153

Evaluation of the Corrosion Behavior and Hardness of Glucose-Carburized Steel in Comparison with Fe₂B Borided Layers
p.159

Evaluation of Properties of Selected Coatings on Steel C60E in Terms of their Use in Gearing
p.166

Preparation of Novel Corona-Resistance Polyimide/Spherical SiO₂ Hybrid Films
p.172

HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 716Preparation of Interface-Cross-Linked Micelles as...

Preparation of Interface-Cross-Linked Micelles as Drug Delivery via RAFT Polymerization

Abstract:

Block copolymer PLA₂₀₀-b-PPEGMEMA₂₂₅ were prepared via ring-open polymerization and RAFT process. Further stabilization of the micellar system was performed in water using a dimethacrylate (EDGMA), and the RAFT to cross-link the interface. The interface-cross-linked micelle was found to present better properties than the uncross-linked block copolymer micelle during the drug loading and releasing experiment. Both block copolymers and cross-linked micelles show no toxicity on COS-7 cell line.

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Periodical:

Advanced Materials Research (Volume 716)

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147-152

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.716.147

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Online since:

July 2013

Authors:

Jian Ping Li, Lian Lai Cui, Xin Tan, Ling Zhang

Keywords:

Drug Delivery, Interface-Cross-Linking, Micelles, RAFT

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