Thermo-Responsive Supramolecular Hybrid Hydrogels Formed by Graphene Oxide-Grafted-Poly(Ethylene Glycol) and α-Cyclodextrin

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Abstract:

Poly(ethylene glycol) methyl ether-grafted-graphene oxide (GO) was synthesized by a coupling reaction and formed inclusion complexes (ICs) after selective threading of the mPEG segments of the GO-mPEG through the cavities of α-cyclodextrins (α-CDs) units. The polypseudorotaxane structures of the as-obtained hydrogels were confirmed by X-ray diffraction, TGA, DSC, and SEM. The complexation of the mPEG segments with α-CDs and the hydrogen-bond interaction between CDs resulted in the formation of supramolecular hybrid hydrogels with a strong network. The resultant hybrid hydrogels were found to be thermo-responsive, and could be applied as a promising drug delivery system.

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Advanced Materials Research (Volumes 718-720)

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172-175

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July 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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[1] Liu, Z. F., Liu, Q., Huang, Y., et al, Organic Photovoltaic Devices Based on a Novel Acceptor Material: Graphene, Adv. Mater. 20 (2008) 3924-3930.

DOI: 10.1002/adma.200800366

Google Scholar

[2] Hasan EA, Cosgrove T, Round AN, Nanoscale thin film ordering produced by channel formation in the inclusion complex of alpha-cyclodextrin with a polyurethane composed of polyethylene oxide and hexamethylene , Macromolecules. 41 (2008) 1393-1400.

DOI: 10.1021/ma071484n

Google Scholar

[3] Li J, Ni X, Leong K, Block-selected molecular recognition and formation of polypseudorotaxanes between poly(propylene oxide)-poly (ethylene oxide)poly(propylene oxide) triblock copolymers and alpha-cyclodextrin , Angew Chem Int Ed, 42 (2003) 69-72.

DOI: 10.1002/anie.200390055

Google Scholar

[4] Chung JW, Kang TJ, Kwak SY, Supramolecular self-assembly of architecturally variant alpha-cyclodextrin inclusion complexes as building blocks of hexagonally aligned microfibrils, Macromolecules, 40 (2007) 4225-4234.

DOI: 10.1021/ma0625105

Google Scholar

[5] Z. Liu, J. T. Robinson, X. Sun, PEGylated nanographene oxide for delivery of water-insoluble cancer drugs, Am. Chem. Soc., 130 (2008) 10876.

DOI: 10.1021/ja803688x

Google Scholar

[6] Y. Liu, D. Yu, C. Zeng, Z. Miao, et al, Biocompatible Graphene Oxide-Based Glucose Biosensors, Langmuir, 26 (2010) 6158-6160.

DOI: 10.1021/la100886x

Google Scholar

[7] Geim, A. K., Novoselov, K. S, The rise of graphene, Nat. Mater. 6 (2007) 183-191.

Google Scholar

[8] Hu S., Zhou M., Kong S.H., et al, et al, Pseudopolyrotaxane Structure Constructed by Polycaprolactone (PCL) Grafted on Multi-walled Carbon Nanotubes and α- cyclodextrins, Adv. Mater. Res. 487 (2012) 668-6716.

DOI: 10.4028/www.scientific.net/amr.487.668

Google Scholar

[9] Pramodh, K. P., Hussain, H. M., Koh, H. R., et al, Covalent bonded polymer–graphene nanocomposites, Polym. Sci. Part A: Polym. Chem. 48 (2010) 4262-4267.

DOI: 10.1002/pola.24212

Google Scholar

[10] Liu, N., Luo, F., Wu, H. X., et al, One-step ionic-liquid-assisted electrochemical synthesis of ionic-liquid-functionalized graphene sheets directly from graphite, Adv. Funct. Mater. 18 (2008) 1518-1528.

DOI: 10.1002/adfm.200700797

Google Scholar