Chronic Effect of Cadmium on Serum Concentrations of Estradiol and Testosterone in Male Rana nigromaculata

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The adult male Rana nigromaculata were exposed to different doses of cadmium for 30d, serum concentrations of the steroid hormones, testosterone and estradiol were examined. Chronic exposure to cadmium caused significant changes both at the testosterone and estradiol levels. Exposure to cadmium resulted in lesser serum testosterone concentrations and more estradiol in 0.05 and 0.1 ppm. Although not statistically significant, frogs exposed to 0.2 ppm had smaller drop in testosterone and significant more estradiol. The results suggest that cadmium exhibited the non-monotonic dose-response relationship with the serum hormone concentrations, testosterone and estradiol.

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Advanced Materials Research (Volumes 726-731)

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54-57

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August 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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